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A study of 113 patients with chronic simple glaucoma showed immediate IOP increases up to 20 mm Hg upon challenge (exposure) with food or other allergens. Another study of three individual cases of simple glaucoma, showed that elimination of food allergens markedly improved treatment outcomes compared to treatment with drugs and surgery or drugs all alone. In one case, intraocular pressure could merely be controlled once allergens were eliminated around the diet. In two other cases, despite adequate control of IOP having a combination of medication and surgery, visual field loss continued to innovation. Visual fields actually improved markedly upon beginning an allergen-free diet. Sjogren was extremely first to identify the relationship between allergy and IOP.
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