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PGF 2 derivatives are employed to medically lower IOP by affecting the FP receptor. These include latanoprost (Xalatan), travoprost (Travatan), bimatoprost (Lumigan) and unoprostone isopropyl (Rescula). Forskolin (Colforsin) works through the complementary IOP-lowering but anti-inflammatory PGE 2 pathway with the c-AMP-mediated EP 2, EP 3 and EP 4 receptors.
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Forskolin definitely is recognized to find qualities that will help in curing heart conditions, asthma, glaucoma, insomnia, allergy symptoms, skin issues, irritable bowel syndrome, bladder problems, and even sexual dysfunction among male. Its main task is directed towards heart muscles because delivers efficient cure to problems related towards the heart.
Regulating intra-cellular communication via prostaglandins has demonstrated superior diurnal IOP therapy for all other glaucoma medication. Coleus forskohlii also regulates intra-cellular communication via c-AMP which mediates most for this effects of prostaglandin PGE 2 (see chart).
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