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Regulating intra-cellular communication via prostaglandins has revealed superior diurnal IOP therapy for all other glaucoma medication. Coleus forskohlii also regulates intra-cellular communication via c-AMP which mediates most of this effects of prostaglandin PGE 2 (see chart).
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Large diurnal fluctuations in IOP during the day or higher consecutive days, such as those using food sensitivities and allergies, are along with an increased risk of for glaucoma progression over and above more traditional risk factors such as age, race and intimate.
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PGF 2 derivatives are used to medically lower IOP by affecting the FP receptor. These include latanoprost (Xalatan), travoprost (Travatan), bimatoprost (Lumigan) and unoprostone isopropyl (Rescula). Forskolin (Colforsin) works located on the complementary IOP-lowering but anti-inflammatory PGE 2 pathway with the c-AMP-mediated EP 2, EP 3 and EP 4 receptors.
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Rhododendron: incipient glaucoma, with alot of pain periodically in and around eye, always worse just before a storm and better once could be clicked begins.
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